Skip to main content

Table 2 Univariate analysis of association between liver stiffness measurement (LSM) and other variables

From: Leflunomide increases the risk of silent liver fibrosis in patients with rheumatoid arthritis receiving methotrexate

 

Beta

95% Confidentialinterval

P-value

Demographic variables

   

Age, years

- 0.145

- 0.054, 0.008

0.140

Body mass index, kg/m2

0.134

- 0.041, 0.227

0.173

Disease duration, weeks

0.090

- 0.001, 0.004

0.362

Laboratory variables

   

C-reactive protein, mg/L

0.051

- 0.019, 0.032

0.608

Erythrocyte sedimentation rate, mm/hr

- 0.147

- 0.026, 0.004

0.135

White blood cell, count/mm3

- 0.071

0.000, 0.000

0.473

Hemoglobin, g/dL

0.050

- 0.232, 0.391

0.612

Platelet count, × 1,000/mm3

- 0.044

- 0.007, 0.004

0.654

Prothrombin time, INR

- 0.056

- 6.729, 3.738

0.572

Glucose, mg/dL

0.001

- 0.034, 0.034

0.995

Blood urea nitrogen, mg/dL

- 0.045

- 0.085, 0.053

0.651

Creatinine, mg/dL

- 0.061

- 2.605, 1.358

0.534

Uric acid. mg/dL

0.148

- 0.058, 0.438

0.132

Aspartate aminotransferase, IU/L

0.146

- 0.014, 0.099

0.136

Alanine aminotransferase, IU/L

0.131

- 0.014, 0.071

0.183

Total protein, mg/dL

0.002

- 0.807, 0.822

0.985

Serum albumin, mg/dL

0.089

- 0.645, 1.741

0.364

Total bilirubin, mg/dL

- 0.048

- 2.135, 1.299

0.630

Alkaline phosphatase, IU/L

- 0.372

- 0.024, 0.017

0.711

Gamma-glutamyltranspeptidase, IU/L

0.249

0.008, 0.058

0.010

Triglyceride, mg/dL

- 0.033

- 0.007, 0.005

0.738

High density cholesterol, mg/dL

- 0.185

- 0.050, - 0.001

0.059

Low density cholesterol, mg/dL

- 0.161

- 0.022, 0.002

0.101

Cumulative dose of medication, mg

   

Methotrexate (105 patients)

0.108

0.000, 0.000

0.273

Leflunomide (53 patients)

0.285

0.000, 0.000

0.038

Sulfasalazine (82 patients)

0.031

0.000, 0.000

0.782

Hydroxychloroquine (65 patients)

0.072

0.000, 0.000

0.567

Prednisolone (89 patients)

0.362

0.000, 0.000

< 0.001

Meloxicam (90 patients)

- 0.012

0.000, 0.000

0.909

Celecoxib (70 patients)

0.182

0.000, 0.000

0.131

  1. INR, international normalized ratio.