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Table 1 Characteristics of primary Sjögren's syndrome, nonprimary Sjögren's syndrome sicca and control subjects

From: Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model

Characteristic pSS (n= 24) Non-pSS sicca (n= 16) Controls (n= 25)
Age (years) 49.0 ± 15.8 52.8 ± 15.4 59.0 ± 12.0
Female:male 21:3 13:3 12:13
Ethnicity 24 Caucasian 16 Caucasian 25 Caucasian
Unstimulated whole saliva (ml/minute) 0.10 ± 0.14 0.12 ± 0.18 NA
Stimulated whole saliva (ml/minute) 0.31 ± 0.35 0.33 ± 0.40 NA
Schirmer's test (mm) 9.2 ± 7.6 14.8 ± 11.7 NA
Focal score 3.5 ± 1.2 0.5 ± 1.0 0
Sjögren's syndrome - A (positive:negative) 23:1 2:14 0:25
Sjögren's syndrome - B (positive:negative) 19:5 0:16 0:25
  1. Data presented as the mean ± standard deviation. All primary Sjögren's syndrome (pSS) and non-pSS sicca patients were subjected to a complete American-European Consensus Group diagnostic work-up. NA, not assessed (in controls being head and neck cancer patients without parotid involvement, no functional tests were performed as all these patients were already scheduled for a neck dissection and functional tests were considered too much of a burden to the patients at that time).