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Table 2 Genes with concordant progression patterns in human and mouse disease

From: Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model

Progression GeneSymbol corHuman p.Human corMouse p.Mouse MM.magenta
+ ADA 0.57 5.5 × 10-7 0.62 9.2 × 10-4 0.70
+ AIF1 0.51 1.6 × 10-5 0.57 3.1 × 10-3 0.67
+ C1QB 0.54 3.2 × 10-6 0.65 4.6 × 10-4 0.71
+ CASP3 0.59 1.8 × 10-7 0.52 8.2 × 10-3 0.59
+ CYBB 0.63 1.6 × 10-8 0.56 3.4 × 10-3 0.82
+ ENTPD1 0.51 1.2 × 10-5 0.62 8.5 × 10-4 0.66
+ GZMA 0.63 1.7 × 10-8 0.70 1.0 × 10-4 0.72
+ GZMK 0.61 5.8 × 10-8 0.55 4.1 × 10-3 0.63
+ HLA-DQB1 0.53 6.0 × 10-6 0.65 5.0 × 10-4 0.48
+ HLA-DRB1 0.53 5.9 × 10-6 0.74 2.6 × 10-5 0.89
+ IFIT1 0.59 2.6 × 10-7 0.59 1.9 × 10-3 0.43
+ ITGAX 0.51 1.2 × 10-5 0.63 6.8 × 10-4 0.68
+ LY86 0.58 4.4 × 10-7 0.53 6.4 × 10-3 0.78
+ PLEKHA2 0.63 1.5 × 10-8 0.52 7.1 × 10-3 0.87
+ STAT1 0.67 7.2 × 10-10 0.64 5.2 × 10-4 0.60
+ TLR7 0.63 1.6 × 10-8 0.63 6.6 × 10-4 0.61
- ALDH3A2 -0.50 1.8 × 10-5 -0.63 8.0 × 10-4 -0.64
- ANGPTL4 -0.50 1.9 × 10-5 -0.58 2.6 × 10-3 -0.40
- ATP1B1 -0.56 1.0 × 10-6 -0.58 2.5 × 10-3 -0.62
- CPT1A -0.54 4.0 × 10-6 -0.76 8.7 × 10-6 -0.55
- FAF1 -0.54 4.1 × 10-6 -0.55 4.5 × 10-3 -0.58
- NEO1 -0.52 9.6 × 10-6 -0.53 6.9 × 10-3 -0.47
- PALMD -0.50 2.2 × 10-5 -0.64 6.1 × 10-4 -0.65
- PDHA1 -0.58 3.9 × 10-7 -0.63 8.0 × 10-4 -0.71
- PPFIBP2 -0.56 1.2 × 10-6 -0.57 3.2 × 10-3 -0.48
  1. corHuman denotes the correlation of the gene with human progression status (defined as 0 for controls, 1 for sicca, and 2 for primary Sjögren's syndrome). corMouse denotes the correlation of the gene with mouse progression status (weeks). p.Human and p.Mouse report the correlation test P values in human and mouse data, respectively. MM.magenta reports the module membership value of the gene.