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Table 1 Interleukin (IL)-17A-inducible genes as determined by microarray analysis of fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA)

From: IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis

Accession numbers Full name Symbol Folds increased
NM_000584.2 interleukin 8 IL8 509.5
NM_004591.1 chemokine (C-C motif) ligand 20 CCL20 382.0
NM_002993.2 chemokine (C-X-C motif) ligand 6 CXCL6 314.1
NM_000600.1 interleukin 6 IL6 120.6
NM_001511.1 chemokine (C-X-C motif) ligand 1 CXCL1 88.6
NM_007115.2 tumor necrosis factor, alpha-induced protein 6 TNFAIP6 21.1
NM_002089.1 chemokine (C-X-C motif) ligand 2 CXCL2 20.4
NM_002982.3 chemokine (C-C motif) ligand 2 CCL2 20.0
NM_005623.2 chemokine (C-C motif) ligand 8 CCL8 17.5
NM_002421.2 matrix metallopeptidase 1 MMP1 16.1
NM_001078.2 vascular cell adhesion molecule 1 VCAM1 15.2
NM_000201.1 intercellular adhesion molecule 1 ICAM1 9.3
NM_001565.1 chemokine (C-X-C motif) ligand 10 CXCL10 8.2
NM_001012632.1 interleukin 32 IL32 4.3
NM_002006.3 fibroblast growth factor 2 FGF2 2.7
  1. Bead array gene expression analysis of FLSs and IL-17 activated FLSs from patients with RA (RA FLS) at 12 h. After serum starvation for 24 h, the RA FLSs were stimulated with IL-17A (20 ng/ml) or without IL-17A. Total RNA from RA FLSs was used for the Bead array gene expression analysis. The genes differentially expressed between the IL-17 activated RA FLSs and the RA FLSs were identified by ANOVA with a P-value < 0.01.