Predictors of use of pain medications for persistent knee pain after primary Total Knee Arthroplasty: a cohort study using an institutional joint registry

Table 2 Univariate predictors of use of non-steroidal anti-inflammatory drugs after primary total knee arthroplasty

	Univariate analysis, 2-year follow-up			Univariate analysis, 5-year follow-up
	Odds ratio	(95% CI)	P-value	Odds ratio	(95% CI)	P-value
Male gender (reference female)	0.51	(0.42, 0.63)	< 0.001^a	0.66	(0.52, 0.85)	0.001^a
Age (reference ≤ 60 yrs)
> 60 to 70 yrs	0.78	(0.62, 0.99)	0.04^a	0.59	(0.41, 0.80)	0.001^a
> 70 to 80 yrs	0.60	(0.47, 0.76)	< 0.001^a	0.54	(0.39, 0.73)	< 0.001^a
> 80 yrs	0.52	(0.35, 0.77)	0.001^a	0.95	(0.61, 1.49)	0.84
Body mass index (reference < 25 kg/m²)
25.0 to 29.9	1.15	(0.85, 1.70)	0.30	1.13	(0.77, 1.63)	0.54
30.0 to 34.9	1.17	(0.84, 1.62)	0.35	1.02	(0.72, 1.74)	0.92
35.0 to 39.9	1.67	(1.17, 2.38)	0.005^a	0.85	(0.54, 1.36)	0.50
≥ 40.0	2.32	(1.61, 3.35)	< 0.001^a	1.50	(0.91, 2.48)	0.11
Deyo-Charlson index (5-point change)	1.06	(0.83, 1.36)	0.62	0.88	(0.65, 1.19)	0.40
Depression (reference no depression)	1.93	(1.51, 2.47)	< 0.001^a	1.85	(1.32, 2.60)	< 0.001^a
Anxiety (reference no anxiety)	1.58	(1.14, 2.19)	0.006^a	1.13	(0.69, 1.85)	0.62

ISSN: 1478-6362