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Table 3 Serum levels of APRIL and activity score from the renal histological outcomes.

From: APRIL, a proliferation-inducing ligand, as a potential marker of lupus nephritis

Percentage of glomeruli with the lesions Blood APRIL≤4 ng/ml Blood APRIL > 4 ng/ml P value
Endocapillary proliferation 40.99 ± 6.76 64.87 ± 8.6 0.033*
Fibrinoid necrosis 4.69 ± 2.15 12.66 ± 4.1 0.012*
Neutrophil infiltration 16.47 ± 4.85 49.59 ± 8.95 0.004*
Hyaline deposit 22.74 ± 7.37 27.65 ± 7.36 0.609
Cellular crescent 12.38 ± 3.49 15.12 ± 4.27 0.620
  1. *The cutoff level for blood APRIL was 4 ng/ml. This cutoff value was obtained from the average blood levels of APRIL from all patients studied. APRIL, a proliferation-inducing ligand.