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Table 2 Inflammation and osteoblast-associated genes over-expressed in proteoglycan-induced spondylitis (PGISp) spines

From: Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors

Gene Fold change PGISp/Control P-value Gene symbol
Matrix metallopeptidase 3 5.29 3.50E-05 Mmp3
Matrix metallopeptidase 13 2.26 0.0086 Mmp13
Tissue inhibitor of metalloproteinase 1 3.48 0.0003 Timp1
Interleukin 1, beta 1.57 0.0087 Il1b
Interleukin 1 receptor, type II 1.28 0.0000 Il1r2
interleukin 28 receptor alpha 1.18 0.0068 Il28ra
Signal transducer and activator of transcription 1 1.18 0.0150 Stat1
Signal transducer and activator of transcription 3 1.21 0.0039 Stat3
Bone sialoprotein 2.62 0.0001 Ibsp
Collagen Type I 2.51 0.0005 Col1a1
Collagen Type III 2.42 0.0004 Col3a1
Osteocalcin 1.50 0.0297 Bglap1