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Table 3 Reasons for non-adherence to the treatment advice of the treat-to-target strategy

From: Adherence to a treat-to-target strategy in early rheumatoid arthritis: results of the DREAM remission induction cohort

 

Remission

(DAS28 < 2.6)

(n= 553)

Non-remission

(DAS28 ≥ 2.6)

(n= 539)

Tapering off/discontinuing instead of continuing

40 (7.2)

 

   Unknown

12

 

   Patient wish

3

 

   Side effects

19

 

   Clinical remission

5

 

   Other

1

 

Continuing instead of tapering off/discontinuing

34 (6.2)

.

   Unknown

23

 

   Patient wish

4

 

   Active disease

5

 

   Other

2

 

Intensifying instead of not intensifying*

24 (4.3)

.

   Unknown

2

 

   Patient wish

2

 

   Active disease

20

 

Not intensifying* instead of intensifying

.

188 (34.9)

   Unknown

 

29

   Patient wish

 

13

   Side effects

 

32

   Clinical remission

 

106

   Other

 

8

Other deviations from treatment advice

10 (1.8)

39 (7.2)

   Unknown

5

10

   Patient wish

.

2

   Side effects

4

16

   Clinical remission

.

2

   Other

1

9

  1. Data are presented of a total of 1097 visits of 100 patients with early rheumatoid arthritis, stratified by remission state according to the Disease Activity Score in 28 joints (DAS28). Values regarding the type of deviation are presented as number (%), values regarding the reasons for non-adherence are presented as number. *Including continuing, tapering off and discontinuing medication.