Figure 3From: Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener's granulomatosisProteinase-3 (PR-3) mRNA is expressed in pneumocytes type II in normal lung tissue (arrows). The expression of PR-3 mRNA was detected by nonradioactive in situ hybridization, and the pneumocytes type II were characterized by double-labeling with fluorescent lectins of Maclura pomifera (magnification, 60 × 2.5).Back to article page