Figure 4From: Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener's granulomatosisProteinase-3 (PR-3) mRNA is expressed in macrophages (arrows). Some cells express the PR-3 mRNA detected by nonradioactive in situ hybridization and double-labeling with CD68, a marker for macrophages (magnification, 40 × 2.5).Back to article page