The role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study

Table 2 Regression analysis between general characteristics, disease-related characteristics, classical cardiovascular disease risk factors and the SEVR

	Primary cohort	Validation cohort
General characteristics
Age	β = 0.02, P = 0.79	β = 0.03, P = 0.73
Gender	0.97 (0.96 to 0.99)*	0.98 (0.96 to 0.99)*
Disease-related characteristics
Log disease duration	*β =* 0.21, p = 0.01	β = 0.12, P = 0.21
RF positivity	0.90 (0.99 to 1.02)	n/a
Log ESR	*β = -* 0.20, P = 0.01	β= -0.144, P = 0.131
Log CRP	*β = -* 0.23, P = 0.003	*β = -* 0.28, P = 0.002
DAS28	β = -0.12, P = 0.09	n/a
HAQ	β = -0.11, P = 0.16	n/a
Classical CVD risk factors
Body mass index	β = - 0.13, P = 0.05	β = - 0.19, P = 0.18
Pulse pressure	*β = -* 0.23, P = 0.004	*β = -* 0.21, P = 0.017
Mean blood pressure	β = -0.10, P = 0.15	β = -0.17, P = 0.05
Heart rate	*β =* -0.64, P < 0.001	*β = -* 0.76 P < 0.001
Total cholesterol	β = -0.12, P = 0.09	β = -0.14, P = 0.14
TC:HDL ratio	β = -0.02, P = 0.76	β = -0.09, P = 0.35
Triglycerides	β = -0.01, P = 0.90	β = 0.01, P = 0.94

Data presented as β and P values or odds ratio (95% confidence interval). CRP, C reactive protein; CVD, cardiovascular disease; DAS28, Disease Activity Score in 28 joints; ESR, erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; HDL, high density lipoprotein; n/a, not available; RF, rheumatoid factor; SEVR, subendocardial viability ratio; TC, total cholesterol. *P < 0.001. Bold data represent statistically significant results.