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Table 4 Generalised estimating equations testing the effect of time on various measurements.

From: The role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study

  CRPa ESRa DAS28 SEVRa MBPa AIx
Significance of change over time      
   P value < 0.001 0.004 < 0.001 0.30 0.002 < 0.001
Baseline       
   Meanb 8.7 (5.7 to 13.2) 16.8 (11.3 to 25.0) 4.3 (0.17) 153.3 (142.1 to 165.5) 98.9 (95.2 to 102.8) 31.9 (1.56)
2 weeks       
   Meanb 4.2 (2.8 to 6.4) 10.8 (7.4 to 15.9) 2.8 (0.26) 154.8 (144.9 to 165.3) 94.4 (90.2 to 98.8) 30.2 (1.74)
   P valuec < 0.001 < 0.001 < 0.001 0.69 0.010 0.11
3 months       
   Meanb 5.5 (3.7 to 8.3) 11.4 (6.9 to 18.9) 2.8 (0.27) 160.4 (149.6 to 172.0) 92.9 (88.0 to 98.1) 32.3 (1.98)
   P valuec < 0.001 0.05 < 0.001 0.14 0.003 0.75
1 year       
   Meanb 2.8 (1.6 to 5.1) 11.9 (7.9 to 17.7) 2.6 (0.29) 154.1 (140.5 to 169.1) 92.7 (87.3 to 98.5) 29.6 (2.15)
   P valuec < 0.001 0.33 < 0.001 0.85 0.002 0.13
  1. AIx, augmentation index; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; DAS28, Disease Activity Score in 28 joints; MBP, mean blood pressure; SEVR, subendocardial viability ratio. From a generalised estimating equation, with unstructured correlation structure. aLog10-transformed prior to analysis. bData displayed as geometric mean (95% confidence interval) or mean (standard error) as applicable. cVersus baseline. Bold data represent statistically significant results.