| CRPa | ESRa | DAS28 | SEVRa | MBPa | AIx |
---|---|---|---|---|---|---|
Significance of change over time | Â | Â | Â | Â | Â | |
   P value | < 0.001 | 0.004 | < 0.001 | 0.30 | 0.002 | < 0.001 |
Baseline | Â | Â | Â | Â | Â | Â |
   Meanb | 8.7 (5.7 to 13.2) | 16.8 (11.3 to 25.0) | 4.3 (0.17) | 153.3 (142.1 to 165.5) | 98.9 (95.2 to 102.8) | 31.9 (1.56) |
2 weeks | Â | Â | Â | Â | Â | Â |
   Meanb | 4.2 (2.8 to 6.4) | 10.8 (7.4 to 15.9) | 2.8 (0.26) | 154.8 (144.9 to 165.3) | 94.4 (90.2 to 98.8) | 30.2 (1.74) |
   P valuec | < 0.001 | < 0.001 | < 0.001 | 0.69 | 0.010 | 0.11 |
3 months | Â | Â | Â | Â | Â | Â |
   Meanb | 5.5 (3.7 to 8.3) | 11.4 (6.9 to 18.9) | 2.8 (0.27) | 160.4 (149.6 to 172.0) | 92.9 (88.0 to 98.1) | 32.3 (1.98) |
   P valuec | < 0.001 | 0.05 | < 0.001 | 0.14 | 0.003 | 0.75 |
1 year | Â | Â | Â | Â | Â | Â |
   Meanb | 2.8 (1.6 to 5.1) | 11.9 (7.9 to 17.7) | 2.6 (0.29) | 154.1 (140.5 to 169.1) | 92.7 (87.3 to 98.5) | 29.6 (2.15) |
   P valuec | < 0.001 | 0.33 | < 0.001 | 0.85 | 0.002 | 0.13 |