| |
GG
|
GA+AA
| |
---|
|
Number
|
(n= 138)
|
(n= 64 + 6)
|
P-value
|
---|
Age, years, mean (SD)
| |
52 (13)
|
50 (13)
|
0.21
|
Female gender, n (%)
| |
89 (64%)
|
50 (71%)
|
0.32
|
RF positivity, n (%)
| |
105 (76%)
|
55 (79%)
|
0.69
|
DAS28, mean (SD)
|
Baseline
|
208
|
5.2 (1.4)
|
5.3 (1.3)
|
0.38
|
3-year average
|
208
|
4.0 (1.1)
|
3.9 (1.0)
|
0.85
|
6-year average
|
159
|
4.0 (1.0)
|
3.7 (1.0)
|
0.10
|
9-year average
|
115
|
4.0 (1.0)
|
3.7 (1.0)
|
0.12
|
Patients with erosions at baseline, n (%)
|
208
|
76 (55%)
|
44 (63%)
|
0.28
|
Ratingen score, median (range)
|
Baseline
|
208
|
0 (0-2)
|
0 (0-2)
|
0.17
|
3 years
|
208
|
7 (0-15)
|
4 (0-10)
|
0.08
|
6 years
|
160
|
12 (2-26)
|
10 (1-21)
|
0.18
|
9 years
|
116
|
22 (10-38)
|
14 (3-24)
|
0.07
|
- Percentages are expressed in relation to the total number of patients for each genotype group. RF, rheumatoid factor; DAS28, 28-joint disease activity score.