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Table 1 Demographics of the inception cohort (n = 208)

From: Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis

   GG GA+AA  
  Number (n= 138) (n= 64 + 6) P-value
Age, years, mean (SD)   52 (13) 50 (13) 0.21
Female gender, n (%)   89 (64%) 50 (71%) 0.32
RF positivity, n (%)   105 (76%) 55 (79%) 0.69
DAS28, mean (SD)
Baseline 208 5.2 (1.4) 5.3 (1.3) 0.38
3-year average 208 4.0 (1.1) 3.9 (1.0) 0.85
6-year average 159 4.0 (1.0) 3.7 (1.0) 0.10
9-year average 115 4.0 (1.0) 3.7 (1.0) 0.12
Patients with erosions at baseline, n (%) 208 76 (55%) 44 (63%) 0.28
Ratingen score, median (range)
Baseline 208 0 (0-2) 0 (0-2) 0.17
3 years 208 7 (0-15) 4 (0-10) 0.08
6 years 160 12 (2-26) 10 (1-21) 0.18
9 years 116 22 (10-38) 14 (3-24) 0.07
  1. Percentages are expressed in relation to the total number of patients for each genotype group. RF, rheumatoid factor; DAS28, 28-joint disease activity score.