Table 5 Subgroup analysis: identification and management of abnormal CRFs

Smoking

Abnl (n)

36

36

48

56

ID

6 (17%)

29 (81%)

40 (83%)

49 (88%)

< 0.0001

0.7

0.4

MA

5 (14%)

20 (56%)

25 (52%)

34 (61%)

0.0004

0.7

0.7

Weight

Abnl (n)

160

160

222

162

ID

41 (26%)

72 (45%)

176 (79%)

92 (57%)

0.0004

< 0.0001

0.04

MA

13 (8%)

49 (31%)

151 (68%)

74 (46%)

< 0.0001

< 0.0001

0.006

SBP

Abnl (n)

132

132

199

150

ID

119 (90%)

131 (99%)

198 (99.9%)

149 (99%)

0.001

0.9

1

MA

12 (9%)

44 (33%)

146 (73%)

64 (43%)

< 0.0001

< 0.0001

0.1

DBP

Abnl (n)

45

45

45

52

ID

43 (96%)

45

45

52

0.5

1

1

MA

8 (18%)

18 (40%)

35 (78%)

30 (58%)

0.04

< 0.001

0.1

HDL

Abnl (n)

26

26

75

33

ID

2 (8%)

11 (42%)

56 (75%)

22 (67%)

0.009

< 0.01

0.07

MA

1 (4%)

4 (15%)

38 (51%)

13 (39%)

0.3

< 0.0001

0.08

LDL

Abnl (n)

39

39

102

33

ID

1 (3%)

23 (59%)

85 (83%)

26 (79%)

< 0.0001

0.009

0.08

MA

1 (3%)

16 (41%)

76 (75%)

21 (64%)

< 0.0001

0.0009

0.06

TG

Abnl (n)

53

53

130

54

ID

6 (11%)

31 (59%)

110 (85%)

36 (67%)

< 0.0001

< 0.0003

0.4

MA

3 (6%)

17 (32%)

86 (66%)

20 (37%)

0.0009

< 0.0001

0.7

FBG

Abnl (n)

26

26

141

36

ID

0

12 (46%)

135 (96%)

16 (44%)

< 0.0001

< 0.0001

1

MA

0

2 (8%)

132 (94%)

8 (22%)

0.5

< 0.0001

0.2