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Table 2 Genotype distributions and allele frequencies of OPN polymorphisms in OA and control subjects

From: OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population

OPN polymorphism Allele frequency OA patients, n % Controls, n % Global P-value Adjusted OR 95% CI Adjusted P-value
-156/G/GG GG 203 27.07 213 26.83 0.557 1    
  GGG 352 46.93 391 49.24   0.956 0.732 1.276 0.701
  GGGG 195 26.00 190 23.93   1.787 0.887 1.552 0.674
  G 758 50.53 817 51.45 0.318 1    
  GG 742 49.47 771 48.55   1.038 0.785 1.267 0.658
-443C/T CC 167 22.27 119 14.99 < 0.001 1    
  CT 384 51.20 405 51.01   0.763 0.457 0.998 0.003
  TT 199 26.53 270 34.01   0.525 0.392 0.872 < 0.001
  C 718 47.87 643 40.49 0.018 1    
  T 782 52.13 945 59.51   0.689 0.575 0.896 < 0.001
-66T/G TT 188 25.07 153 19.27 0.013 1    
  TG 369 49.20 402 50.63   0.738 0.516 0.988 0.035
  GG 193 25.73 239 30.10   0.657 0.494 0.874 0.017
  T 745 49.67 708 44.58 0.009 1    
  G 755 50.33 880 55.42   0.876 0.765 0.876 0.011
  1. OPN, osteopontin; OA, osteoarthritis; OR, odds ratio.