Figure 1
From: The role of statins as potential targets for bone formation
Cultures of murine neonatal calvaria incubated for either 4 or 7 days in the presence of simvastatin at 1 μM. Small amounts of new bone are present in control cultures whereas cultures exposed to simvastatin for 4 days show marked new bone formation and osteoblast accumulation. Cultures exposed for 7 days show further enhancement of bone formation.