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Table 1 Breeding of Col2CreER;Mmp13fx/fx mice (Mmp13Col2ER).

From: MMP13 is a critical target gene during the progression of osteoarthritis

Breeding

Desired progeny

a) Col2CreER x Mmp13fx/fx

a) Col2CreER;Mmp13fx/wt

b) Col2CreER;Mmp13fx/wt x Mmp13fx/fx

b) Col2CreER;Mmp13fx/fx

c) Col2CreER;Mmp13fx/fx x Mmp13fx/fx

c) Col2CreER;Mmp13fx/fx and Mmp13fx/fx