From: Predictors of Chikungunya rheumatism: a prognostic survey ancillary to the TELECHIK cohort study
Outcomes (versus recovery as reference) | Relapsing rheumatic musculoskeletal pain | Lingering rheumatic musculoskeletal pain | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Determinants | N | CIR, % | Adjusted odds ratio | 95% CI | P- value | N | CIR, % | Adjusted odds ratio | 95% CI | P- value |
Gender | 0.536 | 0.562 | ||||||||
Male | 41 | 34.7 | 1 | 48 | 31.9 | 1 | ||||
Female | 70 | 32.4 | 0.78 | 0.34, 1.74 | 102 | 42.2 | 0.78 | 0.33, 1.82 | ||
Age | 0.013 | < 0.001 | ||||||||
15 to 29 yrs | 19 | 27.3 | 1 | 12 | 20.7 | 1 | ||||
30 to 44 yrs | 32 | 37.9 | 1.60 | 0.57, 4.51 | 28 | 30.4 | 1.64 | 0.51, 5.31 | ||
45 to 59 yrs | 27 | 30.0 | 2.67 | 0.78 - 9.10 | 52 | 50.2 | 5.62 | 1.52, 20.79 | ||
≥ 60 yrs | 33 | 36.3 | 9.20 | 2.31, 36.59 | 58 | 55.6 | 16.03 | 3.82, 67.13 | ||
Underlying comorbidity | 0.667 | 0.555 | ||||||||
None | 56 | 32.8 | 1 | 62 | 32.5 | 1 | ||||
Metabolic syndrome without rheumatic disorders* | 35 | 31.8 | 1.45 | 0.45, 4.65 | 63 | 53.6 | 1.92 | 0.59, 6.24 | ||
Rheumatic disorders with or without metabolic syndrome** | 6 | 33.5 | 1.67 | 0.20, 13.53 | 16 | 53.8 | 2.11 | 0.27, 16.26 | ||
Other conditions¶ | 12 | 44.7 | 2.02 | 0.62, 6.49 | 8 | 18.8 | 2.02 | 0.60, 6.81 | ||
Initial rheumatic involvement | 0.008 | 0.001 | ||||||||
Low to moderate† | 70 | 31.8 | 1 | 77 | 31.0 | 1 | ||||
Severe‡ | 41 | 35.6 | 3.52 | 1.40, 8.87 | 73 | 50.0 | 5.43 | 1.95, 15.11 | ||
CHIKV-specific IgG titre (per one unit increase) | 111 | 33.2 | 3.31 | 1.82, 5.99 | < 0.001 | 150 | 38.3 | 5.72 | 2.74, 12.51 | < 0.001 |
Exposure Score # | 0.132 | 0.195 | ||||||||
First quartile class (-2.526; -0.415) | 21 | 32.3 | 1 | 32 | 38.7 | 1 | ||||
Second quartile class (-0.400; 0.018) | 27 | 31.9 | 0.60 | 0.20, 1.73 | 33 | 33.2 | 0.48 | 0.16, 1.42 | ||
Third quartile class (0.026; 0.432) | 23 | 27.0 | 0.53 | 0.17, 1.70 | 35 | 41.7 | 0.70 | 0.22, 2.13 | ||
Fourth quartile class (0.433; 1.435) | 25 | 38.3 | 2.09 | 0.57, 7.59 | 39 | 42.6 | 1.87 | 0.43, 7.97 |