Haplotype blocks described in the region Chr21:44529072..44541978 of the HapMap Project in the CEU and the JPT populations. The linkage disequilibrium (LD) solid spine approach was used to define haplotype blocks. Standard color-coding was used for LD plots: white (r2 = 0), shaded gray (0 <r2 < 1), black (r2 = 1). Squares without a number indicate D' = 1. CEU, Utah residents with Northern and Western European ancestry from the CEPH collection; JPT, Japanese in Tokyo, Japan.