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Table 5 Comparison of treatment data between lupus nephritis patients with and without renal TMA

From: The spectrum of renal thrombotic microangiopathy in lupus nephritis

  LN with renal TMA LN without renal TMA P-value
Number of patients (%) 36 112  
Treatment    
PE (Number of patients (%)) 19 (52.8) 7 (6.25) <0.001
MP (Number of patients (%)) 26 (72.2) 18 (16.1) <0.001
P 36 (100) 112 (100) 1
CYC 30 (83.3) 88 (78.6) 0.536
AZA 1 (2.8) 5 (4.5) 1
MMF 3 (83.3) 11 (9.8) 1
LEF 2 (5.6) 8 (7.1) 1
Treatment response    
CR 8 (22.2) 30 (26.8) 0.586
PR 12 (33.3) 65 (58.0) 0.01
TF 16 (44.4) 17 (15.2) <0.001
Duration of follow-up (m) 53 (6,240) 53 (6,282) 0.15
Relapse rate 4 (4/20, 20%, 3 with nephritic relapse and 1 with proteinuric relapse) 17 (17/95, 17.89%, 15 with nephritic relapse and 2 with proteinuric relapse) 0.543
  1. AZA, azathioprine; CR, complete remission; CYC, cyclophosphamide; LEF, leflunomide; MMF, mycophenolate mofetil; MP, methylprednisolone impulse; P, oral prednisone; PE, plasma exchange; PR, partial remission; TF, treatment failure