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Table 4 Risk of developing rheumatoid arthritis: Cox regression univariate and multivariate hazards ratio (HR) analysis

From: Anti-cyclic citrullinated peptide antibody titer predicts time to rheumatoid arthritis onset in patients with undifferentiated arthritis: results from a 2-year prospective study

  HR (95% CI)
Unadjusted
P HR (95% CI)
Adjusted
P
CRP     
Negative 1   1  
Low + 0.720 (0.362, 1.434) 0.350 0.875 (0.423, 1.811) 0.719
High+ 1.737 (1.049, 2.877) 0.032 1.827 (0.950, 3.514) 0.071
RF     
Negative 1   1  
Low+ 2.020 (1.001, 4.073) 0.050 0.791 (0.248, 2.522) 0.692
High+ 3.097 (1.867, 5.137) < 0.001 0.729 (0.219, 2.431) 0.607
ACPA     
Negative 1   1  
Low + 3.360 (1.412, 7.998) 0.006 3.187 (1.257, 8.077) 0.015
High + 4.613 (2.698, 7.887) < 0.001 4.324 (2.023, 9.245) < 0.001
Hand joints arthritis 1.871 (1.083, 3.232) 0.025 2.140 (1.128, 4.059) 0.020
  1. CRP, C-reactive protein; RF, rheumatoid factor; ACPA, anti-citrullinated peptide antibodies.