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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Clinical characteristics in subjects with NLRP3 V198M diagnosed at a single UK center and a review of the literature

Figure 1

Pedigrees of four families with NLRP3 V198M. Family 1 with three members affected by MWS/FCAS/CINCA, family 2 with a proband diagnosed with familial cold autoinflammatory syndrome (FCAS), family 3 with a proband affected by Schnitzler syndrome and family 4 with a proband affected by uncharacterized long-standing systemic inflammatory disorder. Open shapes represent healthy individuals, solid shapes represent affected individuals, and shaded shapes represent asymptomatic carriers; each proband is indicated by an arrow.

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