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Table 4 Fatigue versus adipokines, IGF-1 and neuropeptides

From: Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin?

   FIQ fatigue Adiponectin Leptin Resistin Free IGF-1 Total IGF-1 IGFB3 NPY NGF
MFIGF r
P
n
0.623
<0.001
48
0.107
0.468
48
-0.074
0.618
48
-0.125
0.398
48
0.024
0.871
48
0.254
0.100
43
0.039
0.801
44
0.150
0.464
26
0.141
0.493
26
FIQ Fatigue r
P
n
1.000
48
0.143
0.333
48
-0.345
0.016
48
-0.111
0.451
48
-0.032
0.829
48
0.198
0.203
43
0.155
0.315
44
0.004
0.984
26
-0.412
0.037
26
Adiponectin r
P
n
  1.000
48
0.032
0.827
48
0.123
0.405
48
-0.200
0.172
48
0.148
0.343
43
-0.143
0.355
44
0.245
0.227
26
-0.151
0.460
26
Leptin r
P
n
   1.000
48
0.153
0.300
48
0.131
0.374
48
-0.354
0.020
43
0.082
0.595
44
0.472
0.015
26
0.426
0.030
26
Resistin r
P
n
    1.000
48
-0.103
0.486
48
0.036
0.817
43
-0.043
0.782
44
0.023
0.912
26
0.148
0.470
26
Free IGF-1 r
P
n
     1.000
48
0.366
0.016
43
0.361
0.016
44
0.167
0.414
26
0.401
0.042
26
Total IGF-1 r
P
n
      1.000
43
0.188
0.250
39
0.085
0.706
22
0.233
0.296
22
IGFB3 r
P
n
       1.000
44
0.395
0.046
26
0.198
0.332
26
Neuropeptide Y
(NPY)
r
P
n
        1.000
26
0.340
0.089
26
  1. Correlation between baseline fatigue (FIQ and MFIGF), serum free IGF-1, serum levels of total IGF-1, IGFB3, adipokines and neuropeptides. r, Spearman's correlation coefficient; P, P-value; n, number; MFIGF, Multidimensional Fatigue Inventory subscale of General Fatigue; FIQ, Fibromyalgia Impact Questionnaire; IGF, insulin-like growth factor; IGFB3, insulin-like growth factor-binding protein-3; NGF, nerve growth factor.