Figure 4
From: CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice
Changes in lymphocyte subsets during induction of remission and sequential regulatory T cell (Treg) transfer. Average absolute numbers of total lymphocytes (A) and average percentage of CD4+ T cells (B) and CD19+ B cells (C) among lymphocytes in the peripheral blood of (NZBxNZW) F1 mice with active disease before and after induction of remission with glucocorticosteroid (GC)/cyclophosphamide (CTX), and after an additional adoptive transfer of 1.5 × 106 Treg/mouse (Treg) compared to age-matched mice that received only GC/CTX and PBS (Control). Data are the summary of two independent experiments with six to eight mice per group in total. Error bars indicate standard error of the mean (SEM).