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Table 5 Summary of association between region of interest activity and cognitive domain z-scores under formal neuropsychological testing

From: Functional neuronal network activity differs with cognitive dysfunction in childhood-onset systemic lupus erythematosus

fMRI paradigm

Region of interest

Attention

domain

VCA

domain

Working memory domain

Working memory: N-back

Frontal mid inf R

0.51

  
 

Precuneus

0.47

0.54

 
 

Parietal inf R

 

0.45

 

Attention: CTP-IP

Frontal mid L

  

-0.45

 

Insula + temporal sup L

  

-0.46

 

SMA + cingulate mid bilateral

  

-0.47

 

Fusiform +occipital inf L

0.52

  

VCA: match vs. motor contrast

Frontal sup L

 

0.45

 
 

Parietal sup L

 

0.48

 
 

Fusiform + occipital inf R

 

0.45

 
 

Angular R

  

0.51

VCA: SC vs. motor contrast

Frontal mid L

 

0.45

 
 

Frontal sup L

 

0.64

 
 

Frontal sup R

0.49

0.65

 
 

Precuneus bilateral

0.54

0.62

 
 

Parietal sup L

0.50

0.56

 
 

Parietal sup R

0.48

  
 

Fusiform + occipital inf L

 

0.52

 
 

Fusiform + occipital inf R

 

0.48

 
  1. Values are partial correlation coefficients (r-values). Only r- values > 0.45 are shown, corresponding to P < 0.05. fMRI, functional magnetic resonance imaging; CPT-IP: continuous performance task-identical pairs; VCA, visuoconstructive ability; SC, square completion; L, left; R, right; inf, inferior; sup, superior; mid, middle; SMA, supplementary motor area.
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Arthritis Research & Therapy

ISSN: 1478-6362

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