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Supplementary Table 2 Comparison of CD19high patients and CD19low patients of the retrospective study group cohort and the prospective study group cohort.

From: B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response

 

CD19low group

CD19high group

Level of significance

Retrospective study group

n = 58

n = 36

 

   Age (years)

63.8 (56–72)

62.7 (56–72)

0.613

   Disease duration (years)

11.4 (7.1–22.6)

19 (5.8–27.7)

0.446

   ESR (mm/h)

35.9 (22.83–3.19)

31.52 (21.72–3.9)

0.393

   C-reactive protein (mg/l)

27.6-(6.5–60)

15.7 (7.18–40.28

0.204

   Serum IgM (g/l)

1.65 (1.20–2.26)

1.92 (1.60–2.61)

0.022

   Serum IgG (g/l)

10.45 (9.09–11.70)

10.50 (9.54–13.00)

0.498

   Serum IgA (g/l)

2.67 (1.89–3.73)

2.67 (1.88–3.91)

0.724

   RF IgM (IU/ml)

134.8 (84–257)

187 (110–207)

0.182

   RF IgA 9 IU/ml)

75 (33.5–128.75)

31.5 (13.5–106.5)

0.02

   ANF (titer)

1:160 (0–1:320)

1:160 (0–1:1120)

0.861

   Circulating immune complexes(g/l)

4.6 (3.32–9.15)

4.45 (3–5.8)

0.607

Prospective study group

n = 36

n = 34

 

   C-reactive protein (mg/l)

14 (5–25.5)

5.4 (0–9.2)

0.013

   Serum IgM (g/l)

1.07 (0.79–1.4)

1.19 (0.88–1.43)

0.618

   Serum IgG (g/l)

11.5 (10.22–13.7)

12.7 (11–14.2)

0.371

   Serum IgA (g/l)

3.08 (2.04–3.86)

2.35 (1.78–3.02)

0.062

   RF IgM (IU/ml)

132 (31.1–253)

65.5 (0–136)

0.099

   RF IgA (IU/ml)

63.5 (12–155.8)

0 (0–8)

< 0.001

  1. ANF, antinuclear factors; ESR, erythrocyte sedimentation rate; RF, rheumatoid factor. Data are presented as medians (interquartile ranges) of all parameters, and the resulting level of significance are given.