| Adult-onset DM Mexico City | Adult-onset DM Guadalajara |
---|
Number | 44 | 17 |
Age (mean ± SD) | 46.7 ± 14.1a | 39.9 ± 12.1a |
Male | 32% | 18% |
Autoantibodies | | |
Jo-1 | 4% | 0% |
Mi-2 (95% CI) | 59%b (43.3 to 73.7) | 12%b (1.5 to 36.4) |
p155/140 (95% CI) | 9%c (2.5 to 21.7) | 35%c (14.2 to 61.7) |
MJ/NXP-2 | 4% | 6% |
SAE | 4% | 0% |
SRP | 0% | 6% |
PM-Scl | 2% | 12% |
U1RNP | 2% | 0% |
Negative | 16% | 29% |
Su/Ago2 | 14% | 0% |
Ro60 | 11% | 24% |
Ro52d | 21% | 29% |
- aP = 0.035 by Mann-Whitney; bP = 0.0012; cP = 0.02, by Fisher exact test; dsome samples were not tested due to availability. All were determined by immunoprecipitation except anti-Ro52 determined by ELISA. Anti-EJ, PL-7, PL-12, OJ were not found. DM, dermatomyositis; negative, negative for myositis-specifc/related autoantibodies, anti-Jo-1 to -U1RNP in the table; PM, polymyositis; SAE, small ubiquitin-like modifier activating enzyme; SRP, signal recognition particle.