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Table 2 Prevalence of myositis-specific/related autoantibodies in adult-onset DM

From: Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara

  Adult-onset DM
Mexico City
Adult-onset DM
Guadalajara
Number 44 17
Age (mean ± SD) 46.7 ± 14.1a 39.9 ± 12.1a
Male 32% 18%
Autoantibodies   
   Jo-1 4% 0%
Mi-2
(95% CI)
59%b
(43.3 to 73.7)
12%b
(1.5 to 36.4)
p155/140
(95% CI)
9%c
(2.5 to 21.7)
35%c
(14.2 to 61.7)
   MJ/NXP-2 4% 6%
   SAE 4% 0%
   SRP 0% 6%
   PM-Scl 2% 12%
   U1RNP 2% 0%
   Negative 16% 29%
   Su/Ago2 14% 0%
   Ro60 11% 24%
   Ro52d 21% 29%
  1. aP = 0.035 by Mann-Whitney; bP = 0.0012; cP = 0.02, by Fisher exact test; dsome samples were not tested due to availability. All were determined by immunoprecipitation except anti-Ro52 determined by ELISA. Anti-EJ, PL-7, PL-12, OJ were not found. DM, dermatomyositis; negative, negative for myositis-specifc/related autoantibodies, anti-Jo-1 to -U1RNP in the table; PM, polymyositis; SAE, small ubiquitin-like modifier activating enzyme; SRP, signal recognition particle.