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Table 4 Comparison of percentage of DM, prevalence of anti-Mi-2 and genetic origin in the literature

From: Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara

  Mexico City Guadalajara Texas
  Mestizo Mestizo Mestizo Mestizo Mexican American
  Okada [6] Present study Okada [6] Present study Arnett [4]
PM/DM number 36 67 (46 DM) 38 28 (20 DM) 25
% of DM in PM/DM 79% 69% 79% 71% NA
Anti-Mi-2 in PM/DM
(95% CI)
36%a
(20.8 to 53.8)
43%b, c
(31.2 to 56.0)
13%a
(4.4 to 28.1)
14%b
(4.0 to 32.7)
8%c
(1.0 to 26.0)
Anti-Mi-2 in PM/DM, combined
(95% CI)
41%d, e
(31.2 to 50.9)
14%d
(6.4 to 24.3)
8%e
(1.0 to 26.0)
Anti-Mi-2 in DM
(95% CI)
NA 59%f
(43.2 to 73.0)
NA 15%f
(3.2 to 37.9)
NA
Anti-synthetase in PM/DM 4% 6% 0% 0% 20%
UV index [32] 10.5 to 12.5 10.5 to 12.5 6.5 to 8.5
Genetic admixture estimate [29, 30]      
   African 4% 5% 8%
   European 46% 67% 61%
   Amerindian 50% 28% 31%
  1. aP = 0.03; bP = 0.0088; cP = 0.0012; dP < 0.0001; eP = 0.0018; fP = 0.001. DM, dermatomyositis; PM, polymyositis