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Table 4 Comparison of percentage of DM, prevalence of anti-Mi-2 and genetic origin in the literature

From: Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara

 

Mexico City

Guadalajara

Texas

 

Mestizo

Mestizo

Mestizo

Mestizo

Mexican American

 

Okada [6]

Present study

Okada [6]

Present study

Arnett [4]

PM/DM number

36

67 (46 DM)

38

28 (20 DM)

25

% of DM in PM/DM

79%

69%

79%

71%

NA

Anti-Mi-2 in PM/DM

(95% CI)

36%a

(20.8 to 53.8)

43%b, c

(31.2 to 56.0)

13%a

(4.4 to 28.1)

14%b

(4.0 to 32.7)

8%c

(1.0 to 26.0)

Anti-Mi-2 in PM/DM, combined

(95% CI)

41%d, e

(31.2 to 50.9)

14%d

(6.4 to 24.3)

8%e

(1.0 to 26.0)

Anti-Mi-2 in DM

(95% CI)

NA

59%f

(43.2 to 73.0)

NA

15%f

(3.2 to 37.9)

NA

Anti-synthetase in PM/DM

4%

6%

0%

0%

20%

UV index [32]

10.5 to 12.5

10.5 to 12.5

6.5 to 8.5

Genetic admixture estimate [29, 30]

     

   African

4%

5%

8%

   European

46%

67%

61%

   Amerindian

50%

28%

31%

  1. aP = 0.03; bP = 0.0088; cP = 0.0012; dP < 0.0001; eP = 0.0018; fP = 0.001. DM, dermatomyositis; PM, polymyositis