Table 1 Characteristics of the 60 patients with systemic sclerosis included in the discovery cohort
From: Correlations between angiogenic factors and capillaroscopic patterns in systemic sclerosis
Age (years), median (range) | 53.5 (28-81) |
Disease duration (years), median (range) | 9 (1-50) |
Limited/Diffuse cutaneous subset, n (%) | 36 (60)/24 (40) |
Modified Rodnan skin score > 14, n (%) | 19 (32) |
History of digital ulcers, n (%) | 29 (47) |
Pulmonary fibrosis on CT scan, n (%) | 28 (47) |
Pulmonary arterial hypertension on RHC, n (%) | 4 (7) |
Positive antinuclear antibodies (> 1/160), n (%) | 53 (88) |
Positive antitopoisomerase-1 antibodies, n (%) | 28 (47) |
Positive anticentromere antibodies, n (%) | 12 (20) |
FVC < 75% predicted, n (%) | 13 (22) |
DLCO/AV < 75% predicted, n (%) | 23 (38) |
Treatment with calcium channel blockers, n (%) | 60 (100) |
Treatment with angiotensin-converting enzyme inhibitors, n (%) | 19 (32) |
Treatment with endothelin-receptor antagonists and/or PDE5 inhibitors, n (%) | 12 (20) |