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Table 2 Nailfold videocapillaroscopy patterns and endothelial marker levels in peripheral blood or serum of patients with systemic sclerosis included in the discovery cohort

From: Correlations between angiogenic factors and capillaroscopic patterns in systemic sclerosis

  Capillaroscopy pattern P value
  Early
Median (range)
Active
Median (range)
Late
Median (range)
 
EPCs (106 Lin-mononuclear cells) 61 (29-573) 82 (21-300) 31 (5-300) < 0.0001
CECs (106 Lin-mononuclear cells) 81 (10-342) 36 (5-155) 77 (6-472) 0.4
VEGF (pg/ml) 518 (161-1,028) 493 (156-1,146) 814 (189-1,564) 0.01
PlGF (pg/ml) 9.6 (4.6-24.2) 9.9 (0.7-19.6) 10.5 (2.3-26.5) 0.8
sVCAM-1 (ng/ml) 766 (482-1,828) 694 (354-1,405) 767 (459-1,314) 0.4
Tie-2 (ng/ml) 24.4 (12.9-29.4) 21.1 (14.1-27.1) 22.2 (16-39.6) 0.3
Endostatin (ng/ml) 185 (88-477) 139 (54-178) 150 (22-662) 0.3
Endoglin (CD105) (ng/ml) 3.7 (1.9-5.0) 3.9 (2.8-5.6) 3.5 (2.6-5.1) 0.5
Endothelin-1 (pg/ml) 1.5 (1.0-3.6) 2.5 (0.9-7.2) 1.7 (0.4-3.1) 0.02
Angiopoietin-2 (pg/ml) 2,166 (1241-3,312) 2,016 (1,249-4,027) 2202 (1,512-5,148) 0.5
von Willebrand factor antigen (%) 180 (95-266) 169 (69-304) 170 (83-302) 0.9