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Table 1 Matrix metalloproteinase 2 (MMP-2) shRNA sequences

From: MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc

Sequence name

Top and bottom "stem-loop-stem" sequences, 5 to 3

shMMP2a

CACCGCTGAAGGACACCCTCAAGAACGAATTCTTGAGGGTGTCCTTCAGC

 

AAAAGCTGAAGGACACCCTCAAGAATTCGTTCTTGAGGGTGTCCTTCAGC

shMMP2b

CACCGCCGGGATAAGAAGTATGGATTCTCGAAAGAATCCATACTTCTTATCCCGG

 

AAAACCGGGATAAGAAGTATGGATTCTTTCGAGAATCCATACTTCTTATCCCGGC

shMMP2c

CACCGCTGTGTTCTTCGCAGGGAATCGAAATTCCCTGCGAAGAACACAGC

 

AAAAGCTGTGTTCTTCGCAGGGAATTTCGATTCCCTGCGAAGAACACAGC

shMMP2d

CACCGCAATACCTGAACACTTTCTACGAATAGAAAGTGTTCAGGTATTGC

 

AAAAGCAATACCTGAACACTTTCTATTCGTAGAAAGTGTTCAGGTATTGC

shMMP2e

CACCGTGGTGGTCACAGCTATTTCTTCCGAAGAAGAAATAGCTGTGACCACCA

 

AAAATGGTGGTCACAGCTATTTCTTCTTCGGAAGAAATAGCTGTGACCACCAC

shNon

CACCGCCGATTAGCTGATCGTGCTTAGTCGAAACTAAGCACGATCAGCTAATCGG

 

AAAACCGATTAGCTGATCGTGCTTAGTTTCGACTAAGCACGATCAGCTAATCGGC

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Arthritis Research & Therapy

ISSN: 1478-6362

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