Figure 5
From: Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism
TGF-β1 secretion is decreased by A 2A R activation at earlier time points and restored after 24 hours. NHDF cells were serum-starved and incubated with CGS-26180 1 µM at the indicated time periods and released TGF-β1 levels were analyzed by ELISA. Data represent means ± S.E.M. from four independent experiments. Statistics were performed by unpaired-t test, ***P <0.001, **P <0.01, vs. non-stimulated control.