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Table 1 Epidemiologic, laboratory and capillaroscopic features of the two early systemic sclerosis series

From: Early systemic sclerosis: marker autoantibodies and videocapillaroscopy patterns are each associated with distinct clinical, functional and cellular activation markers

Feature Rheumatology Unit (n= 45) Angiology Unit (n= 26) Pvalue
Sex (female/male ratio) 43/2 22/4 NS
Age (years) 41 (17-73) 37.5 (16-71) NS
RP duration (years) 3 (0.5-24) 3 (1-20) NS
Subset 1: antibody-positive, NVC-positive 26 (57.8) 6 (2.2) 0.0098
Anti-Scl-70 antibody-positive 5 (19.2) 0  
   ACA-positive 19 (73.1) 3 (50)  
   Anti-RNA polymerase III antibody-positive 2 (7.7) 3 (50)  
   Megacapillaries only 21 (80.8) 3 (50)  
   Avascular areas ± megacapillaries 5 (19.2) 3 (50)  
Subset 2: antibody-positive, NVC-negative 16 (35.6) 0 -
   AntiScl-70 antibody-positive 4 (25) 0  
   ACA-positive 12 (75) 0  
   Anti-RNA polymerase III antibody-positive 0 0  
Subset 3: antibody-negative, NVC-positive 3 (6.7) 20 (76.9) 0.0001
   Megacapillaries only 3 (100) 20 (100) -
   Avascular areas ± megacapillaries 0 0 -
  1. All data expressed as median (range) or number (percentage). ACA, anticentromere antibody; NVC, nailfold videocapillaroscopy; RP, Raynaud's phenomenon.