Characteristica | sCD163 | sCD163/sTWEAK | ||||
---|---|---|---|---|---|---|
 | High* (n= 13) | Normal (n= 76) | P-value | High* (n= 29) | Normal (n= 60) | P-value |
Age, years | 56.08 ± 16.11 | 57.42 ± 11.67 | NS | 59.38 ± 12.86 | 56.18 ± 12.01 | NS |
Disease duration, years | 8.23 ± 6.91 | 11.66 ± 9.29 | NS | 11.53 ± 7.81 | 10.23 ± 9.55 | NS |
Duration of RP (data available for 54 patients), years | 11.46 ± 8.04 | 9.11 ± 8.58 | NS | 10.36 ± 7.55 | 9.32 ± 8.82 | NS |
DSSc, n/total | 5/13 (38.46%) | 15/76 (19.74%) | NS | 10/29 (34.48%) | 10/60 (16.67%) | 0.055 |
mRSS (data available for 72 patients) | 10.92 ± 9.78 | 7.95 ± 6.58 | NS | 12.30 ± 9.68 | 6.63 ± 4.85 | 0.0085 |
ILD, n/total | 9/13 (69.23%) | 46/76 (60.53%) | NS | 17/29 (58.6%) | 38/60 (63.33%) | NS |
PH, n/total (data available for 81 patients) | 2/13 (15.39%) | 2/68 (2.94%) | NS | 2/29 (6.90%) | 2/52 (3.85%) | NS |
FVC (data available for 75 patients), % of predicted | 86.33 ± 19.89 | 94.56 ± 21.61 | NS | 95.42 ± 23.40 | 92.37 ± 20.26 | NS |
DLCO (data available for 53 patients), % of predicted | 74.38 ± 22.94 | 80.10 ± 30.32 | NS | 73.16 ± 24.73 | 82.19 ± 30.97 | NS |
PASP (data available for 56 patients), mmHg | 32.86 ± 12.03 | 29.23 ± 10.99 | NS | 29.00 ± 9.25 | 30.13 ± 12.23 | NS |
Digital ulcers, n/total | 1/13 (7.69%) | 37/76 (46.68%) | 0.005 | 5/29 (17%) | 33/60 (55%) | 0.0006 |
Anti-topo I, n/total | 4/13 (30.77%) | 31/76 (40.79%) | NS | 10/29 (35%) | 25/60 (41.67%) | NS |
ACA, n/total | 3/13 (23.08%) | 30/76 (39.47%) | NS | 9/29 45%) | 24/60 (40%) | NS |
ESR (data available for 51 patients), mm/h | 28.18 ± 21.05 | 21.78 ± 19.27 | NS | 19.64 ± 11.47 | 24.49 ± 21.93 | NS |
Arterial hypertension, n/total | 2/13 (15.39%) | 6/76 (7.90%) | NS | 3/29 (10.35%) | 5/60 (8.33%) | NS |
CCBs, n/total Pentoxyphylline, n/total ACEIs, n/total Sildenafil, n/total NSAIDs, n/total | 3/13 (23.08%) 5/13 (38.46%) 4/13 (30.77%) 1/13 (7.69%) 3/13 (23.08%) | 25/76 (32.90%) 29/76 (38.16%) 8/76 (10.53%) 3/76 (3.95%) 10/76 (13.16%) | NS NS NS NS NS | 8/29 (27.58%) 7/29 (24.14%) 4/29 (13.79%) 1/29 (3.45%) 4/29 (13.79%) | 19/60 (31.67%) 26/60 (43.33%) 8/60 (13.33%) 3/60 (5.00%) 9/60 (15.00%) | NS NS NS NS NS |