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Table 1 Clinical and laboratory characteristics of patients with granulomatosis with polyangiitis (GPA) at the time of blood sampling

From: Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA)

Characteristic

Value

Patients, number

42

Male/female, number

26/16

Age, mean ± SD (range), years

59 ± 14 (28, 81)

Localized/generalized GPA, number

15/27

Positive/negative for PR3-ANCA†, number

23/19

Receiving/not receiving treatment††, number

11/31

Relapses, median (range), number

0 (0, 5)

Disease duration, median (range), months

112 (20, 334)

  1. †Patients were considered to be ANCA-positive when ANCA-titres by IIF were greater than 1:40. ††Four patients were treated with azathioprine only, one with mycophenolate mofetil, and six patients received prednisolone in combination with azathioprine. GPA, granulomatosis with polyangiitis; PR3, proteinase 3; ANCA, antineutrophil cytoplasmic antibody.