Figure 1From: Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndromeCommon (>5% frequency) P2RX7 haplotypes identified in the study population. Grey squares represent the major alleles and black squares the minor alleles, for each single nucleotide polymorphism. Numbering of polymorphisms are based on the original mRNA sequence [Y09561.1; GenBank]. Six major haplotypes were identified with a combined frequency of 70%.Back to article page