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Table 2 ACR classification criteria for patients with normal and decreased ability to degrade NETs

From: Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

ACR classification criteria Normal
(n= 41)
number (%)
Decreased at least once (n= 28)
number (%)
P-value (Pearson)
Malar rash 27 (66%) 19 (68%) 0.86
Discoid rash 12 (30%) 6 (21%) 0.47
Photosensitivity 30 (73%) 12 (43%) 0.01*
Oral ulcer 8 (20%) 8 (29%) 0.38
Arthritis 32 (78%) 23 (82%) 0.68
Serositis 18 (44%) 17 (61%) 0.17
Nephritis 19 (46%) 16 (57%) 0.38
Neurological disorder 2 (5%) 1 (4%) 0.79
Hematological disorder 21 (51%) 17 (61%) 0.44
Immunological disorder 27 (66%) 26 (93%) 0.009*
Anti-dsDNA 22 (54%) 23 (82%) 0.01*
Anti-Sm 4 (10%) 3 (11%) 0.90
False positive Wasserman 5 (12%) 1 (4%) 0.21
Anti-nuclear antibodies 41 (100%) 28 (100%) -
  1. American College of Rheumatology (ACR) classification criteria reflect the clinical history of systemic lupus erythematosus (SLE) and are compared for patients who always displayed normal ability to degrade neutrophil extracellular traps (NETs) compared to patients who at least once displayed a decreased ability to degrade NETs. Asterisks indicate significant differences with the increased proportion highlighted by bold numbers.