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Table 3 Parameters associated with decreased ability to degrade NETs

From: Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

 

approximately 60 days before

Simultaneously

approximately 60 days after

Clinical

Proteinuria

Proteinuria

Proteinuria

manifestations

 

Pyuria

Pyuria

  

Cellular casts

Alopecia

   

Fever

Laboratory

Anti-DNA

Anti-DNA

Anti-DNA

variables

Anti-Histones

Anti-Histones

Leukopenia

 

Anti-Cardiolipin

Anti-Cardiolipin

 
 

Elevated CRP

Leukopenia

 
 

Low C3

Low C1q, C3 and C4

 

Medications

No HCa

No HCa

No HCa

 

Immunosuppressants

 

Immunosuppressants

  1. Manifestations that occur significantly more frequently than expected, before, simultaneously or after the time point with decreased ability to degrade neutrophil extracellular traps (NETs).
  2. aHC, hydroxychloroquine