Serological identification of fast progressors of structural damage with rheumatoid arthritis

Table 2 Univariate correlation between clinical markers and baseline serum C1M

	Baseline (all)			Δ24 weeks (PBO)			Δ24 weeks (PBO w/o escape)			Δ52 weeks (PBO w/o escape)
	ρ	P	N	ρ	P	n	ρ	P	n	ρ	P	n
Age	-0.06	ns	585	-	-	-	-	-	-	-	-	-
BMI	0.01	ns	578	-	-	-	-	-	-	-	-	-
Disdur	-0.01	ns	584	-	-	-	-	-	-	-	-	-
CRP	0.80	<0.0001	584	-0.31	0.001	112	-0.31	0.0023	93	-0.36	0.0007	83
VAS pain	0.21	<0.0001	578	-0.08	ns	110	-0.05	ns	91	-0.00	ns	83
HAQ	0.21	<0.0001	535	-0.17	ns	98	-0.15	ns	82	-0.11	ns	76
DAS28	0.24	<0.0001	573	0.09	ns	108	0.15	ns	89	0.11	ns	77
JSN	0.12	0.0056	556	0.08	ns	153	0.16	ns	90	0.21	0.055	84
mTSS	0.14	0.0006	556	0.19	0.017	153	0.28	0.0084	90	0.34	0.0017	84
ERN	0.15	0.0003	556	0.19	0.019	153	0.13	ns	90	0.21	0.054	84

BMI, Body mass index; DisDur, Disease duration;CRP, C-reactive protein; DAS28-ESR, Disease activity score 28-ESR; HAQ, Health assessment questionnaire; JSN, Joint space narrowing; mTSS, modified total Sharp score; PBO, placebo group; VAS pain, Visual analog scale of pain. Spearman rank correlation coefficient ρ, the P-values and n are provided.

ISSN: 1478-6362