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Table 4 Odds ratios for radiographic progression when combining high and low level of C1M and CRP

From: Serological identification of fast progressors of structural damage with rheumatoid arthritis

C1M/CRP High/High vs. Low/Low High/Low vs. Low/Low Low/High vs. Low/Low Only C1M
JSN OR 3.61 2.37 1.95 3.15
  95% CI 1.62 to 8.01 0.59 to 9.44 0.39 to 9.77 1.50 to 6.58
  P 0.0018 0.22 0.42 0.0023
mTSS OR 3.55 1.79 1.94 2.94
  95% CI 1.97 to 6.41 0.60 to 5.33 0.58 to 6.49 1.71 to 5.05
  P <0.0001 0.30 0.28 0.0001
  1. The high and low levels of the biomarkers were based on the median value of all patients at baseline. C1M, Type I collagen degraded by MMPs; CI, confidence interval; CRP- C-reactive protein; JSN, joint space narrowing; mTSS, modified total Sharp score; OR, odds ratio