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Table 4 Variables associated with measures of atherosclerosis in systemic sclerosis patients after age adjustment.

From: Ischemic arterial events and atherosclerosis in patients with systemic sclerosis: a population-based case-control study

  Plaques (n= 52) IMT ABI
  Odds ratio
(95% CI)
Pvalue β-coefficient Pvalue β-coefficient P value
Age 1.09 (1.05-1.14) <0.0001 0.66 <0.0001 -0.20 0.03
Associations after adjustment for age
Gender female 0.39 (0.12-1.18) 0.1 -0.19 0.0001 -0.12 0.2
ACA+ 2.9 (1.2-7.5) 0.02 -0.01 0.9 -0.14 0.2
Digital ulcers 2.6 (1.1-6.6) 0.03 0.10 0.2 -0.09 0.4
Kidney disease 11.5 (1.7-232) 0.03 -0.05 0.5 0.05 0.6
Disease activity 1.6 (1.04-2.5) 0.03 0.10 0.2 -0.34 0.0004
Disease severity 1.3 (1.1-1.5) 0.005 0.12 0.1 0.13 0.2
Waist-hip ratio 2.6 (0.01-645) 0.7 0.09 0.2 0.19 0.04
Ever smoked 2.5 (1.05-6.7) 0.04 0.10 0.2 0.24 0.01
Systolic BP 1.0 (1.0-1.1) 0.02 0.28 0.0008 -0.06 0.6
Diastolic BP 1.1 (1.0-1.1) 0.008 0.13 0.1 -0.02 0.9
Interleukin-6 3.5 (1.5-9.3) 0.003 0.12 0.1 -0.13 0.2
VCAM-1 9.4 (1.8-58.3) 0.008 -0.05 0.5 0.03 0.8
ICAM-1 0.32 (0.05-1.98) 0.2 0.16 0.04 -0.12 0.2
eGFR 0.4 (0.2-0.99) 0.04 0.11 0.2 -0.04 0.7
  1. IMT, intima-media thickness; ABI, ankle-brachial index; CI, confidence interval; ACA, anticentromere antibodies; +, positivity; BP, blood pressure; VCAM-1, vascular cell adhesion molecule 1; ICAM-1, intercellular adhesion molecule 1; eGFR, estimated glomerular filtration rate, based on cystatin C measurements.