Ischemic arterial events and atherosclerosis in patients with systemic sclerosis: a population-based case-control study

Table 5 Multivariable adjusted model for occurrence of carotid plaques.

	Plaques
Functional groups and included variables	Odds ratio (95% CI)	Pvalue
Age	1.1 (1.03-1.16)	0.003
Disease characteristics
ACA+	4.0 (1.26-14.1)	0.02
Traditional risk factors
Diastolic blood pressure (mmHg)	1.1 (1.01-1.11)	0.04
Inflammatory biomarkers
IL-6 (pg/ml)	3.8 (1.3-13.3)	0.01
Endothelial biomarkers
VCAM-1 (ng/ml)	1.5 (0.15-14.7)	0.7
Kidney function test
eGFR (mL/min/1.73 m²)	0.3 (0.04-1.07)	0.07

CI, confidence interval; ACA, anticentromere antibodies; +, positivity; IL, interleukin; VCAM-1, vascular cell adhesion molecule 1; eGFR, estimated glomerular filtration rate, based on cystatin C measurements.

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