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Table 6 Ischemic arterial events and surrogate measures of atherosclerosis in ACA+ patients versus ACA-patients and controls.

From: Ischemic arterial events and atherosclerosis in patients with systemic sclerosis: a population-based case-control study

  Occurrence of events and atherosclerosis ACA+ vs. ACA- ACA+ vs. controls
  ACA+
(n= 34)
ACA-
(n= 77)
Controls
(n= 105)
Odds ratio**
(95% CI)
Pvalue** Odds ratio*
(95% CI)
Pvalue*
Any arterial event % (n) 32 (11) 11 (9) 7 (7) 5.1 (1.57-18.6) 0.01 8.5 (2.6-31.7) 0.0003
IHD % (n) 18 (6) 9 (7) 4 (4) 2.6 (0.7-10.0) 0.2 4.8 (1.2-20.7) 0.02
ICVD % (n) 6 (2) 3 (2) 3 (3) 4.0 (0.4-49.0) 0.2 2.0 (0.2-13.9) 0.6
IPVD % (n) 18 (6) 4 (3) 1 (1) 9.1 (1.6-79.1) 0.01 70.1 (6.5-2524) <0.0001
Plaque % (n) 65 (22) 39 (30) 41 (43) 3.1(1.2-8.5) 0.02 2.8 (1.1-7.6) 0.04
     β-coefficient   β-coefficient  
IMT mm 0.69 ± 0.13 0.68 ± 0.13 0.68 ± 0.13 0.03 0.7 0.01 0.6
ABI 1.1(1.03-1.2) 1.1 (1.17-1.2) 1.1 (1.07-1.2) -0.12 0.08 -0.14 0.07
  1. Distributions are given as %, median (interquartile range) or mean ± standard deviation. **adjusted for age, sex and disease duration; *adjusted for age and sex. ACA, anticentromere antibodies; +, positivity; -, negativity; CI, confidence interval; IHD, ischemic heart disease; ICVD, ischemic cerebrovascular disease; IPVD, ischemic peripheral vascular disease; IMT, intima-media thickness; ABI, ankle-brachial index.