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Table 3 HLA-DRB1 alleles classified according to du Montcel et al.

From: The phenotype and genotype of rheumatoid arthritis in the Democratic Republic of Congo

du Montcel classification

Amino acid sequence positions 70 to 74

HLA-DRB1

Patient group % (n)

Controls % (n)

SE

OR

95% CI

P-value

S2

QKRAA

*04:01

4.1 (3)

4.2 (2)

positive

2.6

0.8 to 8.3

0.124

 

DKRAA

*13:03

      

S3P

QRRAA

*01:01/02

14.9 (11)

4.2 (2)

    
 

RRRAA

*10

      

S1

DERAA

*11:02, *13:01/02

81.0 (60)

91.6 (44)

negative

   
 

QARAA

*15

      

S3D

DRRAA

*11:01, *12, *16

      

X

nonXXRAA

*03,*07,*08,*09,*14

      
  1. [14], in RA patients and controls (homozygous alleles are counted double)
  2. OR, odds ratio; RA, rheumatoid arthritis; SE, shared epitope; A, alanin; D, aspartic acid aspartique; E, glutamic acid; K, leucin; Q, glutamin; R, arginin