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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways

Figure 1

Preparation of fHAs. High molecular weight (HMW) hyaluronic acid (HA) was digested with bovine testis hyaluronidase. The resulting fragments were separated on a Bio Gel P10 column. For determination of fragment size fluorophore-assisted carbohydrate electrophoresis (FACE) analysis was performed. In this example, fractions 18, 23, 42, 48 and 64 derived from one HA-preparation were compared with a commercially-available HA standard (Sigma-Aldrich). M, HA standard marker; ds, disaccharide units.

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Arthritis Research & Therapy

ISSN: 1478-6362

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