Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways

Table 1 Details of patients used in the study.

Patient	Pathology	Severity Grade^a	Disc Level
1	DH	4	L4/5
2	SD	5	L4/5
3	DH	5	L4/5
4	DH	5	C5/6
5	DH	5	L5/S1
6	DH	4	L4/5
7	DH	3	L5/S1
8	DH	5	L5/S1
9	DH	4	L4/5
10	DH	4	L4/5
11	DH	5	L4/5
12	DH	4	L4/5
13	DH	3	L2/3
14	DH	4	L5/S1
15	DH	4	L5/S1
16	DH	5	L5/S1
17	DH	3	L5/S1
18	DH	5	L4/5
19	DH	4	L5/S1
20	DH	4	C6/7
21	DH	4	L4/5
22	DH	5	L5/S1

^a The degree of IVD degeneration in patients was assessed prior to surgical intervention by magnetic resonance imaging (MRI) using a 5-level grading system based on Pfirrmann's classification of disc degeneration.
C, cervical; DH, disc herniation; F, female; L, lumber; M, male; S, sacral; SD, segment degeneration

ISSN: 1478-6362