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Table 6 Relationships of disease activity and severity with systemic inflammation in moderately or highly active RA

From: Rheumatoid arthritis is associated with reduced adiposity but not with unfavorable major cardiovascular risk factor profiles and enhanced carotid atherosclerosis in black Africans from a developing population: a cross-sectional study

  C-reactive proteina Interleukin-6a
Disease activity variable Age and sex adjusted model Multivariable adjusted modelb Age and sex adjusted model Multivariable
adjusted modelb
  Partial R P Partial R P Partial R P Partial R P
Swollen jointsa 0.025 0.9 0.113 0.4 -0.260 0.07 -0.246 0.1
Tender jointsa 0.028 0.8 0.014 0.9 -0.131 0.4 -0.120 0.4
Doctor disease activitya 0.100 0.5 0.084 0.6 0.212 0.2 0.232 0.1
Patient disease activity -0.092 0.5 -0.066 0.7 0.222 0.1 0.225 0.2
CDAIa 0.066 0.6 0.111 0.5 0.125 0.4 0.147 0.3
Deformed jointsa 0.041 0.8 0.028 0.8 0.012 0.9 -0.050 0.7
  1. Sixty-one patients had moderate or high disease activity (CDAI > 10). aNon-normally distributed variables that were logarithmically transformed; badditionally adjusted for potential confounders of body mass index, waist:height ratio and angiotensin converting enzyme inhibitors (see Table 3). CDAI, Clinical Disease Activity Index.