Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis

Table 3 Cardiovascular risk factors that differed (P < 0.05) in frequency or extent between OA patients (n = 39) as compared with all RA patients (n = 79) and RA patients in whom insulin sensitivity was determined (n = 39)

Risk factor	OA (n = 39)	RA (n = 79)	RA (n = 39)
Exercise^a	13 (33)	42 (53)	18 (46)
Diabetes^a	1 (3)	9 (11)	4 (10)
QUICKI^b	0.369 (0.356–0.383)	N/A	0.344 (0.332–0.355)
HDL cholesterol (mmol/l)^b	1.68 (1.50–1.85)	1.40 (1.30–1.49)	1.40 (1.30–1.50)
C-reactive protein (mg/l)^c	2.7 (0.3–15.9)	9 (0.5–395)	10 (0.5–146)

QUICKI, Quantitative Insulin Sensitivity Check Index; HDL, high-density lipoprotein. ^aData presented as n (%). ^b Data presented as mean (95% confidence interval). ^cData presented as median (range).

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