TY - JOUR AU - Mizoguchi, Fumitaka AU - Murakami, Yousuke AU - Saito, Tetsuya AU - Miyasaka, Nobuyuki AU - Kohsaka, Hitoshi PY - 2013 DA - 2013/11/25 TI - miR-31 controls osteoclast formation and bone resorption by targeting RhoA JO - Arthritis Research & Therapy SP - R102 VL - 15 IS - 5 AB - Increased activity of osteoclasts is responsible for bone loss and joint destruction in rheumatoid arthritis. For osteoclast development and bone resorption activity, cytoskeletal organization must be properly regulated. MicroRNAs (miRNAs) are endogenous small noncoding RNAs that suppress expression of their target genes. This study was conducted to identify crucial miRNAs to control osteoclasts. SN - 1478-6354 UR - https://doi.org/10.1186/ar4282 DO - 10.1186/ar4282 ID - Mizoguchi2013 ER -