From: Is serum HMGB1 a biomarker in ANCA-associated vasculitis?
Variable | Presentation | Early remissiona | Ongoing remission | Prior to relapse 1 | Relapse 1 | Prior to relapse 2 | Relapse 2 |
---|---|---|---|---|---|---|---|
HMGB1 (ng/ml) | 2.35 (1.48 to 3.15) | 1.69* (0.88 to 2.73) | 2.21 (1.42 to 3.68) | 2.59 (1.61 to 4.09) | 2.56 (0.87 to 4.48) | 3.65 (1.71 to 4.56) | 2.77 (0.91 to 4.86) |
Follow-up period (months) | 0 | 3.0b (3.0 to 6.0) | 11.0b (6.0 to 12.0) | 2.0c (2.0 to 3.0) | 20.0b (13.0 to 41.5) | 2.0c (1.0 to 2.0) | 44.0b (35.2 to 68.5) |
BVAS | 15.0 (12.0 to 23.5) | 0 | 0 | 0 | 12.0 (5.5 to 13.5) | 0 | 11.0 (5.7 to 15.7) |
Number of patients | 52 | 49 | 49 | 15 | 17 | 5 | 6 |